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  1. General Info
  2. Effects Info
  3. Reference
Drug Interaction Details
01. General Information
Pair Name Beta-Elemene, Rapamycin
Phytochemical Name Beta-Elemene (PubChem CID: 6918391 )
Anticancer drug Name Rapamycin (PubChem CID: 5284616 )
Structure of
Phytochemical
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2D MOL 3D MOL
Structure of
Anticancer Drug
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2D MOL 3D MOL
02. Combinatorial Therapeutic Effect(s)
Synergistic Effect
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Enhancing Drug Efficacy
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Combination Pair ID: 710
Pair Name Beta-Elemene, Rapamycin
Disease Info [ICD-11: 2A83] Multiple myeloma Investigative
Gene Regulation Down-regulation Phosphorylation AKT1 hsa207
In Vitro Model FTC-133 Thyroid gland follicular carcinoma Homo sapiens (Human) CVCL_1219
Result We demonstrate that the novel combination of mTOR inhibitor with β-elemene synergistically attenuates tumor cell growth in follicular thyroid cancer, which requires additional preclinical validation.
03. Reference
No. Title Href
1 Combinatorial Antitumor Effect of Rapamycin and β-Elemene in Follicular Thyroid Cancer Cells. Biomed Res Int. 2016;2016:6723807. doi: 10.1155/2016/6723807. Click
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