Pair Name | Beta-Elemene, Rapamycin | ||
Phytochemical Name | Beta-Elemene (PubChem CID: 6918391 ) | ||
Anticancer drug Name | Rapamycin (PubChem CID: 5284616 ) | ||
Structure of Phytochemical |
Download
2D
MOL
3D
MOL
|
||
Structure of Anticancer Drug |
Download
2D
MOL
3D
MOL
|
Pair Name | Beta-Elemene, Rapamycin | |||
Disease Info | [ICD-11: 2A83] | Multiple myeloma | Investigative | |
Gene Regulation | Down-regulation | Phosphorylation | AKT1 | hsa207 |
In Vitro Model | FTC-133 | Thyroid gland follicular carcinoma | Homo sapiens (Human) | CVCL_1219 |
Result | We demonstrate that the novel combination of mTOR inhibitor with β-elemene synergistically attenuates tumor cell growth in follicular thyroid cancer, which requires additional preclinical validation. |
No. | Title | Href |
---|---|---|
1 | Combinatorial Antitumor Effect of Rapamycin and β-Elemene in Follicular Thyroid Cancer Cells. Biomed Res Int. 2016;2016:6723807. doi: 10.1155/2016/6723807. | Click |